| Play | Key Line | Modern Text | Original Text |
| Antony and Cleopatra | AC III.ii.57 | That year indeed he was troubled with a rheum. | That year indeed, he was trobled with a rheume, |
| The Comedy of Errors | CE III.ii.135 | stood in her chin, by the salt rheum that ran between | stood in her chin by the salt rheume that ranne betweene |
| Coriolanus | Cor V.vi.46 | At a few drops of women's rheum, which are | At a few drops of Womens rhewme, which are |
| Hamlet | Ham II.ii.504 | With bisson rheum; a clout upon that head | With Bisson Rheume: A clout about that head, |
| Henry IV Part 2 | 2H4 II.iv.56 | i' good truth, as rheumatic as two dry toasts; you cannot | (in good troth) as Rheumatike as two drie Tostes, you cannot |
| Henry V | H5 II.iii.35 | then he was rheumatic, and talked of the Whore of | then hee was rumatique, and talk'd of the Whore of |
| Henry V | H5 III.v.52 | The Alps doth spit and void his rheum upon! | The Alpes doth spit, and void his rhewme vpon. |
| Julius Caesar | JC II.i.266 | And tempt the rheumy and unpurged air, | And tempt the Rhewmy, and vnpurged Ayre, |
| King John | KJ III.i.22 | Why holds thine eye that lamentable rheum, | Why holdes thine eie that lamentable rhewme, |
| King John | KJ IV.i.33 | Read here, young Arthur. (aside) How now, foolish rheum! | Reade heere yong Arthnr. How now foolish rheume? |
| King John | KJ IV.iii.108 | For villainy is not without such rheum, | For villanie is not without such rheume, |
| Measure for Measure | MM III.i.31 | Do curse the gout, serpigo, and the rheum | Do curse the Gowt, Sapego, and the Rheume |
| The Merchant of Venice | MV I.iii.114 | You, that did void your rheum upon my beard | You that did voide your rume vpon my beard, |
| The Merry Wives of Windsor | MW III.i.44 | raw rheumatic day? | raw-rumaticke day? |
| A Midsummer Night's Dream | MND II.i.105 | That rheumatic diseases do abound; | That Rheumaticke diseases doe abound. |
| Much Ado About Nothing | MA V.ii.75 | quarter in rheum. Therefore is it most expedient for the | quarter in rhewme, therfore is it most expedient for the |
| Othello | Oth III.iv.51 | I have a salt and sorry rheum offends me; | I haue a salt and sorry Rhewme offends me: |
| Richard II | R2 I.iv.8 | Awaked the sleeping rheum, and so by chance | Awak'd the sleepie rhewme, and so by chance |
| Troilus and Cressida | TC V.iii.104 | o' these days; and I have rheum in mine eyes too, and | o'th's dayes: and I haue a rheume in mine eyes too; and |
| The Two Noble Kinsmen | TNK V.iv.8 | The gout and rheum, that in lag hours attend | The Gowt and Rheume, that in lag howres attend |
| The Winter's Tale | WT IV.iv.396 | With age and altering rheums? Can he speak? Hear? | With Age, and altring Rheumes? Can he speake? heare? |