sour (adj.)
bitter, harsh, painful
2H6 III.ii.301 [Queen to herself, as if to the King and Warwick] Heart's discontent and sour affliction / Be playfellows to keep you company!
3H6 V.vii.45 [Edward to all] Farewell, sour annoy!
LLL I.i.300 [Costard to Berowne] welcome the sour cup of prosperity!
R2 IV.i.240 [Richard to all] you Pilates / Have here delivered me to my sour cross
R2 [Percy to King Henry] The ... Abbot of Westminster / With clog of conscience and sour melancholy